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Facts About Ulcerative Colitis (UC) and Lialda

What is Ulcerative Colitis?
UC is a type of bowel disease that produces inflammation and sores or ulcers along the inside lining of the large intestine, also called the bowel, or colon. The sores may interfere with the normal digestive process. Most people with UC need to take prescription medicines to help manage their symptoms.

What is Lialda (Lee-ALL-da)?
Lialda is a prescription medicine for patients with active, mild to moderate ulcerative colitis. Lialda can help you achieve induction of remission.

In clinical trials, many people taking Lialda experienced remission, including:

  • Less rectal bleeding
  • Fewer trips to the bathroom (i.e. fewer bowel movements)
  • Reduced inflammation/an improvement in the inside lining of the colon

Who is Lialda for?
Lialda may be taken by adults 18 years or older who have active, mild to moderate ulcerative colitis.

Who should NOT take Lialda?

Anyone who is allergic to mesalamine or any of the ingredients in Lialda or salicylates such as aspirin

Lialda has not been studied for ulcerative colitis in children younger than 18 years of age

What should I know before starting Lialda?
Tell your doctor if you:

  • Are allergic to sulfasalazine, salicylates or mesalamine
  • Have kidney disease or liver disease
  • Are pregnant, intend to become pregnant or are breastfeeding
  • Are taking non-steroidal anti-inflammatory drugs (NSAIDs)
  • Are taking either of the following medications:
    –   Azathioprine
    –   6-mercaptopurine

Tell your doctor about all your medicines, including over-the-counter drugs, vitamins and herbal products.

What are possible side effects of Lialda?
The most common are:

  • Headache
  • Flatulence
  • Increased liver enzymes
  • Hair loss
  • Itching

How should I take Lialda?

  • Take Lialda exactly as your doctor tells you. Your doctor may tell you to take 2 to 4 tablets once a day
  • Lialda is taken once a day with food
  • Swallow Lialda tablets whole. Do not chew, break or crush them

Where can I get more information about Lialda?

  • Ask your doctor or pharmacist
  • Go to www.Lialda.com
  • Call 1-877-UC FACTS

 

 

 

Important Safety Information

You should not take Lialda if you are allergic to salicylates (including mesalamine or aspirin) or to any of the ingredients of Lialda. Tell your doctor if you have a stomach blockage or are allergic to sulfasalazine. Mesalamine has been associated with a syndrome that may be difficult to distinguish from an ulcerative colitis flare-up. If you experience cramping, abdominal pain, bloody diarrhea, fever, headache or rash, talk to your doctor immediately. Some patients taking mesalamine have reported heart-related hypersensitivity reactions, such as inflammation of the heart muscle and inflammation of the lining of the heart. Tell your doctor if you have problems with your liver or kidneys.

In worldwide clinical trials, Lialda was generally well tolerated. The most common adverse events were headache and flatulence. As with other medications, some serious side effects may occur. Less than 1% of patients experienced inflammation of the pancreas, which led to discontinuation of therapy with Lialda.

Please see Lialda Full Prescribing Information

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Lialda is a trademark of Shire LLC. MMX® is a registered trademark owned by Cosmo Technologies Ltd, Ireland, a wholly-owned subsidiary of Cosmo Pharmaceuticals SpA.

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